Duke Engineers Develop AI Platform to Design Nanoparticles for Drug Delivery
Duke University biomedical engineers have developed TuNa-AI, an AI-powered platform that designs and optimizes nanoparticles for drug delivery, with promising early results in cancer treatment applications.
Biomedical engineers at Duke University have developed TuNa-AI, a platform that combines automated wet lab techniques with artificial intelligence to design and optimize nanoparticles for drug delivery. The system addresses a longstanding bottleneck in pharmaceutical development by considering both ingredient selection and mixture ratios simultaneously. In a proof-of-concept study, the team used TuNa-AI to successfully deliver venetoclax, a difficult-to-encapsulate chemotherapy drug used in leukemia treatment, and reduced potentially harmful excipients in another anti-cancer formulation by 75%. The research was published in ACS Nano.
Read more here: https://phys.org/news/2025-09-ai-nanoparticles-drug-delivery.html